지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.6
- 수록면
- 279 - 285 (7page)
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초록· 키워드
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Prediction of glucose concentration in the interstitial fluid (ISF) based on mid-infrared absorption spectroscopy was examined at the glucose fundamental absorption band of 1000 - 1500/㎝ (10 - 6.67 ㎛) using multi-component analysis. Simulated ISF samples were prepared by including four major ISF components. Sodium lactate had absorption spectra that interfere with those of glucose. The rest NaCl, KCl and CaCl₂ did not have any signatures. A preliminary experiment based on Design of Experiment, an optimization method, proved that sodium lactate influenced the prediction accuracy of glucose. For the main experiment, 54 samples were prepared whose glucose and sodium lactate concentration varied independently. A partial least squares regression (PLSR) analysis was used to build calibration models. The prediction accuracy was dependent on spectrum preprocessing methods, and Mean Centering produced the best results. Depending on calibration sample sets whose sodium lactate had different concentration levels, the standard error prediction (SEP) of glucose ranged 17.19 ~ 21.02 ㎎/dl.
목차
Ⅰ. INTRODUCTION
Ⅱ. EXPERIMENTAL RESULTS
Ⅲ. DISCUSSION AND CONCLUSION
ACKNOWLEDGMENT
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2009-425-018492000