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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.3
- 수록면
- 137 - 141 (5page)
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This study was carried out to investigate the skin and eye irritation of surfactin C in rabbits and skin sensitization of surfactin C in guinea pigs. Skin and eye irritation test were performed in New Zealand white rabbits according to Korea Food and Drug Agency (KFDA) guidelines for toxicological test. Buehler method was applied to evaluate the sensitization potential of surfactin C in Hartley guinea pigs. Surfactin C caused slight conjunctival discharge and redness in rabbits by its mechanical irritation. However, it did not show any skin irritation in rabbits and skin sensitization in guinea pigs. The results indicated that surfactin C was a minimal irritant and non-irritant material on eye and skin, respectively. Moreover, it did not cause any skin sensitization in guinea pigs.
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참고문헌
참고문헌 (19)
참고문헌 신청
1. [학술지(정기간행물)] - Arima, K / 1968 / Surfactin, acrystalline peptidelipid surfactant produced by Bacillus subtilis: isolation, characterization and its inhibition of fibrin clot formation / Biochem. Biophys. Res. Commun 31 : 488 ~ 494
2. [학술지(정기간행물)] - Brown, M.J / 1991 / Biosurfactants for cosmetic applications / Int. J. Cosmet. Sci 13 : 61 ~ 64
3. [학술지(정기간행물)] - Cameotra, S.S / 2004 / Recent applications of biosurfactants as biological and immunological molecules / Curr. Opin. Microbiol 7 : 262 ~ 266
4. [학술지(정기간행물)] - Cooper, D.G / 1979 / Production of surface-active lipids by Corynebacterium lepus / Appl. Environ. Microbiol 37 : 4 ~ 10
5. [학술지(정기간행물)] - Desai, J.D / 1997 / Microbial production of surfactant and their commercial potential / Microbiol. Mol. Biol 61 : 47 ~ 64
2. [학술지(정기간행물)] - Brown, M.J / 1991 / Biosurfactants for cosmetic applications / Int. J. Cosmet. Sci 13 : 61 ~ 64
3. [학술지(정기간행물)] - Cameotra, S.S / 2004 / Recent applications of biosurfactants as biological and immunological molecules / Curr. Opin. Microbiol 7 : 262 ~ 266
4. [학술지(정기간행물)] - Cooper, D.G / 1979 / Production of surface-active lipids by Corynebacterium lepus / Appl. Environ. Microbiol 37 : 4 ~ 10
5. [학술지(정기간행물)] - Desai, J.D / 1997 / Microbial production of surfactant and their commercial potential / Microbiol. Mol. Biol 61 : 47 ~ 64
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