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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.12
- 수록면
- 157 - 163 (7page)
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초록· 키워드
오류제보하기
Objective : Polygonum multiflorum Thunberg (Polygonaceae) has been traditionally used as a tonic and the purgative in China and Korea. The genus Polygonum is a source of a wide range of phenolic compound, flavanoids, anthraquinones, stilbenes and tannins. In this study, three anthraquinones were isolated and quantitative determination of anthraquinones from P multiflorum has been developed for quality standardization.
Methods : Three anthraquinone derivatives were isolated from a methanol extract of the radix of P. multiflorum by the chromatographic separation. Their structures were identified as emodin, physcion and ω-hydroxyemodin on the basis of spectral data (MS, 1H-NMR, 13C-NMR) and chemical analysis. HPLC analysis was performed to determine the contents of emodin, physcion, chrysophanol, rhein and ω-hydroxyemodin in P multiflorum from different specimens were collected from twenty Korean markets.
Results : According to the results, the contents of emodin, physcion, chrysophanol, rhein and ω-hydroxyemodin were 0.145%, 0.434%, 0.016%, 0.026%, 0.030% by HPLC, respectively.
Conclusions : In these results, we have determined the contents of emodin, physcion, chrysophanol, rhein and ω-hydroxyemodin in P. multiflorum, respectively. We hope that this study will contribute to the standardization and quality control of herbal medicine.
Methods : Three anthraquinone derivatives were isolated from a methanol extract of the radix of P. multiflorum by the chromatographic separation. Their structures were identified as emodin, physcion and ω-hydroxyemodin on the basis of spectral data (MS, 1H-NMR, 13C-NMR) and chemical analysis. HPLC analysis was performed to determine the contents of emodin, physcion, chrysophanol, rhein and ω-hydroxyemodin in P multiflorum from different specimens were collected from twenty Korean markets.
Results : According to the results, the contents of emodin, physcion, chrysophanol, rhein and ω-hydroxyemodin were 0.145%, 0.434%, 0.016%, 0.026%, 0.030% by HPLC, respectively.
Conclusions : In these results, we have determined the contents of emodin, physcion, chrysophanol, rhein and ω-hydroxyemodin in P. multiflorum, respectively. We hope that this study will contribute to the standardization and quality control of herbal medicine.
목차
Ⅰ. 서론
Ⅱ. 재료 및 방법
Ⅲ. 결과 및 고찰
Ⅳ. 결론
Ⅴ. 감사의 글
Ⅵ. 참고문헌
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