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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.9
- 수록면
- 281 - 287 (7page)
이용수
초록· 키워드
오류제보하기
Cigarette smoke causes atypical structure of pulmonary and oxidative damage. Therefore, we carried out to determine if exposure to cigarette smoke alters pulmonary structure and anti-oxidant related enzyme in a animal model, when natural product extracts using by Nebulizer. The rat were divided into four groups: H<SUB>2</SUB>O-treated (Control), natural product (Camellia sinensis) extracts-treated (CS), natural product extracts-treated with cigarette smoke-exposed (CS+SM) and cigarette smoke-expose (SM). All groups are similar to Control group in weight, but SM group is lower than the other groups. Microscopic image of the pulmonary structure in SM group showed deleterious alterations in the morphology, but the other groups are maintained in normal structure. In anti-oxidant related enzymes, SOD (superoxide dismutase) and catalase, SM group represents the lowest enzyme activity among all groups. But G6PD (glucose-6-phosphate dehydrogenase) and LPO (lipid peroxidation) is SM group represents the highest enzyme activity among all groups. These result indicate that the natural product extracts is an efficient tissue protective substance against smoke-induced lung injury.
목차
영어초록
서론
재료 및 방법
결과 및 고찰
요약
REFERENCES
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - RF,Beers / 1952 / A spectrophotomertic method for measuring the breakdown of hydrogen peroxids by catalase / J Biol Chem. 195 : 133 ~ 135
[학술지(정기간행물)] - JP,Bridges / 2000 / Pulmonary Surfactant Proteins A and D Are Potent Endogenous Inhibitors of Lipid Peroxidation and Oxidative Cellular Injury / J Biol Chem. 275
[학술지(정기간행물)] - C,Cerami / 1997 / Tobacco smoke is a source of toxic reactive glycation products / Proc Natl Acad Sci USA. 94
[학술지(정기간행물)] - M,Dorger / 2002 / Early Inflammatory Response to Asbestos Exposure in Rat and Hamster Lungs: Role of Inducible Nitric Oxide Synthase / Toxicol Appl Pharmacol. 181 : 93 ~ 105
[학술지(정기간행물)] - B,Frei / 2003 / Antioxidant Activity of Tea Polyphenols In Vivo: Evidence from Animal Studies / Am Soci Nutr Sci. : 3275 ~ 3284
[학술지(정기간행물)] - JP,Bridges / 2000 / Pulmonary Surfactant Proteins A and D Are Potent Endogenous Inhibitors of Lipid Peroxidation and Oxidative Cellular Injury / J Biol Chem. 275
[학술지(정기간행물)] - C,Cerami / 1997 / Tobacco smoke is a source of toxic reactive glycation products / Proc Natl Acad Sci USA. 94
[학술지(정기간행물)] - M,Dorger / 2002 / Early Inflammatory Response to Asbestos Exposure in Rat and Hamster Lungs: Role of Inducible Nitric Oxide Synthase / Toxicol Appl Pharmacol. 181 : 93 ~ 105
[학술지(정기간행물)] - B,Frei / 2003 / Antioxidant Activity of Tea Polyphenols In Vivo: Evidence from Animal Studies / Am Soci Nutr Sci. : 3275 ~ 3284
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