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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2005.9
- 수록면
- 349 - 353 (5page)
이용수
초록· 키워드
오류제보하기
The globin in cytosol receives the heme in mitochondria and folds to the hemoglobin within erythrocyte. Two mechanisms have been proposed that the heme was transfered post-translationally or cotranslationally to the globin. In this research, how the globin in cytosol receives post-translationally the heme from membranes was studied according to pH and phospholipid composition. Globins dissolved in various pH buffer solutions (pH 3~7) were rapidly added into the bulk of egg Phosphatidylcholine 100% or 60% liposomes containing hemin in PH 7 buffer solution. Hemin was very highly transferred to globin at PH 4 and 6. Also, hemin was more efficiently transfered to globin in egg Phosphatidylcholine 100% than in 60% liposomes.
목차
영어초록
서론
재료 및 방법
결과 및 고찰
REFERENCES
참고문헌 (30)
참고문헌 신청
[단행본] - E,Antonini / 1971 / Hemoglobin and myoglobin in their reactionswith ligands / North Holland Publishing. Amsterdam : 44 ~ 45
[학술지(정기간행물)] - M,Bogdanov / 1998 / Phospholipid-assisted protein folding: phosphatidylethanolamine is required at a late step of the conformational maturation of the polytopic membrane protein lactose permease / Embo J. 17 : 5255 ~ 5264
[학술지(정기간행물)] - M,Bogdanov / 1999 / Lipid-assisted protein folding / J Biol Chem. 274
[학술지(정기간행물)] - M,Bogdanov / 1996 / A phospholipid acts as a chaperone in assembly of a membrane transport protein / J Biol Chem. 271
[학술지(정기간행물)] - HF,Bunn / 1987 / Subunit assembly of hemoglobin: an important determinant of hematologic phenotype / Blood 69 : 1 ~ 6
[학술지(정기간행물)] - M,Bogdanov / 1998 / Phospholipid-assisted protein folding: phosphatidylethanolamine is required at a late step of the conformational maturation of the polytopic membrane protein lactose permease / Embo J. 17 : 5255 ~ 5264
[학술지(정기간행물)] - M,Bogdanov / 1999 / Lipid-assisted protein folding / J Biol Chem. 274
[학술지(정기간행물)] - M,Bogdanov / 1996 / A phospholipid acts as a chaperone in assembly of a membrane transport protein / J Biol Chem. 271
[학술지(정기간행물)] - HF,Bunn / 1987 / Subunit assembly of hemoglobin: an important determinant of hematologic phenotype / Blood 69 : 1 ~ 6
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UCI(KEPA) : I410-ECN-0101-2009-510-017356694