지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.10 No.4
- 발행연도
- 2005.12
- 수록면
- 353 - 356 (4page)
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초록· 키워드
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It has been recently reported that boron affects bone metabolism in humans and animals. In this study we examined whether boron affects the proliferation on various cell types, MG-63, HOS, Raw 264.7 and SK-N-SH. When treated with different concentrations of boron (1, 10, 100 μM) for 24 and 48 hr, the proliferation of MG-63 cells was enhanced at 10 μM (p<0.05), for 24 hr. In HOS cells, boron had no effect on cell proliferation at 24 or 48 hr. In addition, treatment of pre-osteoclastic cells (Raw 264.7) with 1, 10, 100 μM boron resulted in no effect on cell proliferation. Proliferation of neuronal cells (SK-N-SH) was enhanced by boron in a concentration dependent manner at low concentrations (0.1, 0.5, 1 μM). Besides proliferation activity, boron has an effect on the enhancement of NO production in SK-N-SH cells in a concentration-dependent manner. These studies showed that boron enhances proliferation of osteoblastic cells (especially MG-63), depending upon the concentration of boron. These results also provide further evidence of the positive effects of boron in neuronal disease.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (21)
참고문헌 신청
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Prockop DJ. 1971. Role of iron in the systhesis of collagen in connective tissue. Fed Proc 30:984-990.
Calhoun NR, Smith JC, Becker KL. 1974. The role of zinc in bone metabolism. Clin Orthop 10: 212-234.
Opsahl W, Zeronian H, Ellison M, Lewis D, Rucker RB, Riggins RS. 1982. Role of copper in collagen cross-linking and its influence on selected mechanical properties of chick bone and tendon. J. Nutr 112: 708-716.
Amstrong TA, Spears JW. 2001. Effect of dietary boron on growth performance, calcium and phosphorus metabolism, and bone mechanical properties in growing barrows. J Anim Sci 79: 3120-3127.
Prockop DJ. 1971. Role of iron in the systhesis of collagen in connective tissue. Fed Proc 30:984-990.
Calhoun NR, Smith JC, Becker KL. 1974. The role of zinc in bone metabolism. Clin Orthop 10: 212-234.
Opsahl W, Zeronian H, Ellison M, Lewis D, Rucker RB, Riggins RS. 1982. Role of copper in collagen cross-linking and its influence on selected mechanical properties of chick bone and tendon. J. Nutr 112: 708-716.
Amstrong TA, Spears JW. 2001. Effect of dietary boron on growth performance, calcium and phosphorus metabolism, and bone mechanical properties in growing barrows. J Anim Sci 79: 3120-3127.
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UCI(KEPA) : I410-ECN-0101-2009-511-015199865