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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2005.6
- 수록면
- 187 - 194 (8page)
이용수
초록· 키워드
오류제보하기
Octachlorostyrene (OCS) is a primarily concerning chemical in many countries because of its persistent and bioaccumulative properties in the environment. OCS is not commercially manufactured or used but it may be produced during incineration or chemical synthetic processes involving chlorinated compounds. There are several reports that OCS was found in the waters, sediments, fish, mussels, and also in human tissues. However, systematic studies on the OCS toxicities are scarce in literature. In this study, we tried to get the gene expression data using medaka DNA chip to identify biomarkers of OCS exposure. Medaka (Oryzias latipes) was exposed to OCS 1 ppm for 2 days and 10 days, respectively. Total RNA was extracted and purified by guanidine thiocyanate method and the Cy3- and Cy5-labelled cDNAs produced by reverse trancription of the RNA were hybridized to medaka microarray. As results, eighty five genes were found to be down-or upregulated by OCS. Some of the genes were listed and confirmed by real-time PCR.
목차
ABSTRACT
서론
재료 및 방법
결과 및 고찰
감사의 글
참고문헌
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - / 1980 / Organochlorine compounds in aquatic environments : 743 ~ 750
[학술지(정기간행물)] - / 1986 / Gas chromatographic/mass spectrometric identification of the major components of non aqueous material from the St : 309 ~ 322
[학술지(정기간행물)] - / 2003 / The distribution of octachlorostyrene in environmental sammples 5 : 619 ~ 625
[학술지(정기간행물)] - / 1999 / Council of Great Lakes Industries A report to the Great Lakes Binational Toxics Strategy OCS Workgroup
[학술지(정기간행물)] - / 1999 / Draft PBT National Action Plan for Octachlorostyrene
[학술지(정기간행물)] - / 1986 / Gas chromatographic/mass spectrometric identification of the major components of non aqueous material from the St : 309 ~ 322
[학술지(정기간행물)] - / 2003 / The distribution of octachlorostyrene in environmental sammples 5 : 619 ~ 625
[학술지(정기간행물)] - / 1999 / Council of Great Lakes Industries A report to the Great Lakes Binational Toxics Strategy OCS Workgroup
[학술지(정기간행물)] - / 1999 / Draft PBT National Action Plan for Octachlorostyrene
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Early life Stage Toxicity of PFOA in the Medaka (Oryzias latipes)
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UCI(KEPA) : I410-ECN-0101-2009-539-017708773