지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2002.2
- 수록면
- 53 - 56 (4page)
이용수
초록· 키워드
오류제보하기
The baculovirus expression vector system (BEVS) is one of the powerful heterologous protein expression systems using insect cells. As a result this has become a hot issue in the field of biotechnology. The advantage of the BEVS is that the large-scale production of heterologous proteins, which undergo posttranslational modification in the endoplasmic reticulum (ER), can be accomplished. Although posttranslational modification of heterologous proteins, insect cells is more similar to mammalian cells than yeast, it is not always identical. Therefore, aggregation and degradation can sometimes occur in the ER. To produce a high level of bioactive heterologous proteins using BEVS in insect cells, the prerequisite is to completely understand the posttranslational conditions that determine how newly synthesized polypeptides are folded and assembling with ER chaperones In the ER lumen. Here, we provide Information on current BEVS problems and the possibility of successful heterologous protein production from mammalian cells.
목차
Abstract
Introduction
Signal peptide processing
Posttranslational modification
BEVS in human cells
Acknowledgement
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A Baculovirus Vector for Transient Protein Expression in Mammalian Cells
한국미생물학회 학술대회논문집
2009 .05
-
New Strategy for Enhancing Heterologous Protein Expression through the Alternating N-terminal Codons
한국미생물학회 학술대회논문집
2014 .04
-
Expression and Application of Heterologous Genes in Saccharomyces cerevisiae
한국미생물학회 학술대회논문집
2003 .05
-
Construction and Characterization of Transformed Insect Cells Expressing Antibacterial Protein or Baculovirus Very Late Factor-1
한국응용곤충학회 학술발표회
2000 .01
-
Expression and Secretion of Heterologous Protein in Yeast
미생물학회지
1992 .04
-
Mouse Dual Ig Domain Containing Cell Adhesion Molecule Protein Expression and Purification Using the Baculovirus Expression Vector System
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2010 .09
-
Expression of Human Hypoxanthine Phosphoribosyltransferase in Insect Cells Using a Baculovirus Vector
The Journal of Microbiology
1995 .03
-
Heterologous Expression of Yeast Prepro-$\alpha$-Factor in Rat Pituitary $GH_3$ Cells
한국동물학회 학술대회
1995 .01
-
Bio-active proteins from insect
생명과학
1991 .10
-
Bio-active Proteins from insects
생명과학
1992 .01
-
Heterologous Expression of DNAJ-like Chaperone for Enhanced Carotenoid Synthesis in Microalgae
한국미생물학회 학술대회논문집
2019 .04
-
재조합 단백질 생산을 위한 소포체 신호전달
생명과학회지
2007 .06
-
Production of Biopharmaceuticals in E. coli: Current Scenario and Future Perspectives
Journal of Microbiology and Biotechnology
2015 .01
-
Protein Expression of the Bombyx mori Decapentaplegic Gene using the Baculovirus Expression Vector System
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2015 .09
-
Construction of Transfer Vectors for Production of Baculovirus Occlusion Bodies that Contain Novel Recombinant Crystal Protein
한국응용곤충학회 학술발표회
2003 .01
-
Endoplasmic Reticulum Stress Responses and Apoptosis
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2012 .09
-
Correlation Between p53 and p21 Proteins Expression and Prognostic Factors Related with Colon Cancer
대한임상검사과학회지
2007 .01
-
Heterologous Expression of a Large-sized Natural Product Biosynthetic Gene Cluster in Streptomyes Species
한국미생물학회 학술대회논문집
2019 .04
-
Construction of a Shuttle Vector for Heterologous Expression of a Novel Fungal α-Amylase Gene in Aspergillus oryzae
Journal of Microbiology and Biotechnology
2015 .01
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-470-013900206