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Cheol-Keun Park 논문수  · 이용수 0 · 피인용수 4

소속기관
대한소화관운동학회(현 대한소화기능성질환.운동학회)
소속부서
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주요 연구분야
의약학 > 임상의학 > 내과학
연구경력
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  • 저자정보 . 논문
  • 공저자 . 저널

저자의 연구 키워드

저자의 연구 키워드
#49.3%). NOX1 and NOX4 proteins had opposite prognostic effects. High NOX1 expression was an independent predictor of both shorter recurrence-free survival
#86.8%) of the 227 HCC cases and low immunoreactivity for NOX4 in 112
#among patients with normal α-fetoprotein levels
#Background/Aims: Nicotinamide adenine dinucleotide phosphate oxidase
#both proteins had prognostic value in HCC patients with normal α-fetoprotein levels or with early-stage HCC.
#Endoscopic polypectomy
#HCC). Uncertainties remain regarding the prognostic relevance of NOX1 and NOX4 protein expression in HCC. Methods: NOX1 and NOX4 protein expression was examined by using immunohistochemistry in tumor tissue from 227 HCC patients who underwent hepatectomy. Results: High immunoreactivity for NOX1 was observed in 197
#high NOX1 expression had unfavorable effects on RFS
#Hyperplastic polyp
#including hepatocellular carcinoma
#Neoplastic transformation
#NOX)-mediated reactive oxygen species contribute to various liver diseases
#OS)
#p<0.01) and shorter OS
#p<0.01) and shorter overall survival
#p=0.01). Low NOX4 expression was an independent predictor of both shorter RFS
#p=0.01). Subgroup analysis showed that
#patients with tumor size ≤5.0 cm and patients in Barcelona Clinic Liver Cancer stage A
#RFS)
#whereas low NOX4 expression had unfavorable effects on both RFS and OS. Conclusions: These findings demonstrated that NOX1 and NOX4 protein expression had opposite prognostic effects for HCC patients. Moreover

저자의 논문

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